Mitochondrial ferredoxin is required for heme A synthesis in Saccharomyces cerevisiae.

Abstract excerpt

Heme A is a prosthetic group of all eukaryotic and some prokaryotic cytochrome oxidases. This heme differs from heme B (protoheme) at two carbon positions of the porphyrin ring. The synthesis of heme A begins with farnesylation of the vinyl group at carbon C-2 of heme B. The heme O product of this reaction is then converted to heme A by a further oxidation of a methyl to a formyl group on C-8. In a previous study...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Aminolevulinic Acid
• Share to Electron Transport Complex IV