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Article

Isolation and functional characterization of mutant ferrochelatases in Saccharomyces cerevisiae.

Biochimie - 1 Jan 1996

Góra M, Chaciñska A, Rytka J, Labbe-Bois R

Abstract excerpt

Ferrochelatase is a mitochondrial inner membrane-bound enzyme that catalyzes the incorporation of ferrous iron into protoporphyrin, the last step in protoheme biosynthesis. It is encoded by the HEM15 gene in the yeast Saccharomyces cerevisiae. Five hem15 mutants causing defective heme synthesis and protoporphyrin accumulation were investigated. The mutations were identified by sequencing the mutant hem15 alleles...

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PMID: 8818224
DOI: 10.1016/0300-9084(96)82647-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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