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Article

Defects in the biosynthesis of mitochondrial heme c and heme a in yeast and mammals.

Biochimica et biophysica acta - 6 Dec 2004

Moraes Carlos T, Diaz Franscisca, Barrientos Antoni

Abstract excerpt

Defects in heme biosynthesis have been associated with a large number of diseases, but mostly recognized in porphyrias, which are neurovisceral or cutaneous disorders caused by the accumulation of biosynthetic intermediates. However, defects in the maturation of heme groups that are part of the oxidative phosphorylation system are now also recognized as important causes of disease. The electron transport chain...

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Identifiers

PMID: 15576047
DOI: 10.1016/j.bbabio.2004.09.002

Genes

COX10
COX15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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