Role in anaerobiosis of the isoenzymes for Saccharomyces cerevisiae fumarate reductase encoded by OSM1 and FRDS1.

doi:10.1002/yea.1467

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Article

Role in anaerobiosis of the isoenzymes for Saccharomyces cerevisiae fumarate reductase encoded by OSM1 and FRDS1.

Yeast (Chichester, England) - 1 May 2007

Camarasa Carole, Faucet Virginie, Dequin Sylvie

Abstract excerpt

Saccharomyces cerevisiae possesses both a cytoplasmic and a mitochondrial fumarate reductase, encoded by FRDS1 and OSM1, respectively. While previous studies have shown that mutants lacking FRDS1 and OSM1 cannot grow under anaerobiosis (Arikawa et al., 1998), the physiological role of fumarate reductase (FR) remains poorly understood. Here, we report that an osm1 frds1 mutant is unable to grow anaerobically, even...

Topics

Acetoin
Anaerobiosis
Blotting, Northern
Flavin-Adenine Dinucleotide
Gene Expression Regulation, Enzymologic
Gene Expression Regulation, Fungal
Isoenzymes
Mutation
Oxidation-Reduction
RNA, Fungal
Saccharomyces cerevisiae
Succinate Dehydrogenase
Succinic Acid
Vitamin K 3

Source

Open in PubMed

Identifiers

PMID: 17345583
DOI: 10.1002/yea.1467

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