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Article

Analysis of Oligomerization Properties of Heme a Synthase Provides Insights into Its Function in Eukaryotes.

The Journal of biological chemistry - 6 May 2016

Swenson Samantha, Cannon Andrew, Harris Nicholas J, Taylor Nicholas G, Fox Jennifer L, Khalimonchuk Oleh

Abstract excerpt

Heme a is an essential cofactor for function of cytochrome c oxidase in the mitochondrial electron transport chain. Several evolutionarily conserved enzymes have been implicated in the biosynthesis of heme a, including the heme a synthase Cox15. However, the structure of Cox15 is unknown, its enzymatic mechanism and the role of active site residues remain debated, and recent discoveries suggest additional...

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Identifiers

PMID: 26940873
DOI: 10.1074/jbc.M115.707539
PMCID: PMC4858986

Genes

COX15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Analysis of Oligomerization Properties of Heme a Synthase Provides Insights into Its Function in Eukaryotes.PMID 26940873Read ↗

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