Article
Saccharomyces cerevisiae glutaredoxin 5-deficient cells subjected to continuous oxidizing conditions are affected in the expression of specific sets of genes.
The Journal of biological chemistry - 26 Mar 2004
Bellí Gemma, Molina María Micaela, García-Martínez José, Pérez-Ortín José E, Herrero Enrique
Abstract excerpt
The Saccharomyces cerevisiae GRX5 gene codes for a mitochondrial glutaredoxin involved in the synthesis of iron/sulfur clusters. Its absence prevents respiratory growth and causes the accumulation of iron inside cells and constitutive oxidation of proteins. Null Deltagrx5 mutants were used as an...
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