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Article

Duration and fitness dependence of quasispecies memory.

Journal of molecular biology - 18 Jan 2002

Ruíz-Jarabo Carmen M, Arias Armando, Molina-París Carmen, Briones Carlos, Baranowski Eric, Escarmís Cristina, Domingo Esteban

Abstract excerpt

The duration and fitness dependence of memory in viral quasispecies evolving in cell culture have been investigated using two genetic markers of foot-and-mouth disease virus (FMDV). In lineages of antigenic variant FMDV RED, which reverted to FMDV RGD, memory FMDV RED genomes were detected after 50 infectious cycles, and memory level was fitness dependent. In growth-competition experiments between a reference...

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Identifiers

PMID: 11786012
DOI: 10.1006/jmbi.2001.5232

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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