Evolution of foot-and-mouth disease virus.

Abstract excerpt

Foot-and-mouth disease virus evolution is strongly influenced by high mutation rates and a quasispecies dynamics. Mutant swarms are subjected to positive selection, negative selection and random drift of genomes. Adaptation is the result of selective amplification of subpopulations of genomes. The extent of adaptation to a given environment is quantified by a relative fitness value. Fitness values depend on the...

Topics

• Amino Acid Sequence
• Animals
• Cattle
• Cell Line
• Evolution, Molecular
• Foot-and-Mouth Disease
• Foot-and-Mouth Disease Virus
• Genome, Viral
• Models, Molecular
• Molecular Sequence Data
• Mutation