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Article

Enforced expression of Bcl-2 selectively perturbs negative selection of dual reactive antibodies.

Developmental immunology - 1 Jan 2001

Notidis E, Hande S, Manser T

Abstract excerpt

We investigated the role of apoptosis in the development of B cell memory by analyzing the (p-azophenylarsonate) Ars response in a line of A strain mice in which expression of human Bcl-2 was enforced in the B cell compartment. Previous studies of the Ars immune response in these A. Bcl-2 mice, demonstrated that a large percentage of the antibodies expressed by the Ars induced memory B cell compartment had...

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Share to Antibodies, Antinuclear
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11785672
DOI: 10.1155/2001/83595
PMCID: PMC2276081

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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