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Article

The community effect and Purkinje cell migration in the cerebellar cortex: analysis of scrambler chimeric mice.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Jan 2002

Yang Huaitao, Jensen Patricia, Goldowitz Dan

Abstract excerpt

The Disabled-1 protein in mouse is known to be an intercellular signaling component of the Reelin molecular pathway that subserves neuronal migration in several structures in the brain and spinal cord. The scrambler mutant mouse, which is phenotypically identical to the reeler mouse, is due to a mutation in the disabled-1 gene (Howell et al., 1997; Sheldon et al., 1997). The Purkinje cells of the cerebellum...

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PMID: 11784791
PMCID: PMC6758652

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