Article
Cajal-Retzius cells regulate the radial glia phenotype in the adult and developing cerebellum and alter granule cell migration.
Neuron - 1 Apr 1997
Soriano E, Alvarado-Mallart R M, Dumesnil N, Del Río J A, Sotelo C
Abstract excerpt
Studies on the reeler mutation have shown that pioneer Cajal-Retzius (CR) cells are involved in neuronal migration in the developing cortex. Here, we use grafting and coculture experiments to investigate the mechanisms by which CR cells govern migration. We show that transplantation of embryonic...
Topics
- Animals
- Animals, Newborn
- Cell Movement
- Cell Transplantation
- Cells, Cultured
- Cerebellum
- Cerebral Cortex
- Embryo, Mammalian
- Fetal Tissue Transplantation
- Mice
- Mice, Inbred Strains
- Mice, Neurologic Mutants
- Neuroglia
- Phenotype