Article
[Alterations in DPC4 gene in pancreatic cancers].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Jul 2001
Gu L, Chen J, Cui Q
Abstract excerpt
OBJECTIVE: To examine the alterations in the DPC4 gene in pancreatic cancers. METHODS: Five pancreatic adenocarcinoma cell lines (P1, P2, P3, P4, and P7) and 11 fresh frozen pancreatic cancer tissues were monitored with polymerase chain reaction (PCR), single-strand conformation polymorphism (SSCP) analysis to demonstrate the sequence of deletion and mutation in 6 exons (1, 2, 3, 4, 8, and 11) of the DPC4 gene....
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