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Article

Mutations of the DPC4/Smad4 gene in neuroendocrine pancreatic tumors.

Oncogene - 8 Apr 1999

Bartsch D, Hahn S A, Danichevski K D, Ramaswamy A, Bastian D, Galehdari H, Barth P, Schmiegel W, Simon B, Rothmund M

Abstract excerpt

Tumors of the endocrine pancreas are extremely rare, and molecular mechanisms leading to their development are not well understood. A candidate tumor suppressor gene, DPC4, located at 18q21, has recently been shown to be inactivated in half of pancreatic adenocarcinoma xenografts. The close anatomical relationship of the exocrine and endocrine pancreas prompted us to determine the role of DPC4 in the...

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Share to Polymorphism, Single-Stranded Conformational

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Genes, Tumor Suppressor

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Source

Identifiers

PMID: 10327057
DOI: 10.1038/sj.onc.1202585

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutations of the DPC4/Smad4 gene in neuroendocrine pancreatic tumors.PMID 10327057Read ↗

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