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Article

Mutations in the X region and core promoter are rare and have little impact on response to interferon therapy for chronic hepatitis B.

Journal of medical virology - 1 Feb 2002

Hannoun Charles, Horal Peter, Krogsgaard Kim, Lindh Magnus

Abstract excerpt

Therapy for chronic hepatitis B with interferon-alpha (IFN) may result in viral clearance and hepatitis B e seroconversion in 30-40% of patients. It is still unclear whether viral genetic variability influences response rates. However, certain core promoter mutations were recently associated with a better response to IFN. In the present study, the entire X region, including the core promoter, of hepatitis B virus...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11782925
DOI: 10.1002/jmv.2127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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