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Article

PKCalpha: a versatile key for decoding the cellular calcium toolkit.

The Journal of cell biology - 14 Aug 2006

Reither Gregor, Schaefer Michael, Lipp Peter

Abstract excerpt

Conventional protein kinases C (cPKCs) play an essential role in signal transduction and are believed to integrate both global Ca(2+) transients and diacylglycerol signals. We provide evidence that PKCalpha is a ubiquitous readout sensor for the cellular Ca(2+) toolkit, including highly restricted elementary Ca(2+) release. Threshold stimulations of cells with Ca(2+)-mobilizing agonists resulted in PKCalpha...

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Identifiers

PMID: 16893971
DOI: 10.1083/jcb.200604033
PMCID: PMC2064258

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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