Article
p23/Tmp21 associates with protein kinase Cdelta (PKCdelta) and modulates its apoptotic function.
The Journal of biological chemistry - 6 May 2011
Wang HongBin, Xiao Liqing, Kazanietz Marcelo G
Abstract excerpt
There is emerging evidence that C1 domains, motifs originally identified in PKC isozymes and responsible for binding of phorbol esters and diacylglycerol, interact with the Golgi/endoplasmic reticulum protein p23 (Tmp21). In this study, we investigated whether PKCδ, a kinase widely implicated in apoptosis and inhibition of cell cycle progression, associates with p23 and determined the potential functional...
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