Article
Genome-wide analysis reveals a complex pattern of genomic imprinting in mice.
PLoS genetics - 6 Jun 2008
Wolf Jason B, Cheverud James M, Roseman Charles, Hager Reinmar
Abstract excerpt
Parent-of-origin-dependent gene expression resulting from genomic imprinting plays an important role in modulating complex traits ranging from developmental processes to cognitive abilities and associated disorders. However, while gene-targeting techniques have allowed for the identification of imprinted loci, very little is known about the contribution of imprinting to quantitative variation in complex traits....
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