Article
The effect of CYP2C19 and CYP2D6 genotypes on the metabolism of clomipramine in Japanese psychiatric patients.
Journal of clinical psychopharmacology - 1 Dec 2001
Yokono A, Morita S, Someya T, Hirokane G, Okawa M, Shimoda K
Abstract excerpt
In this study, the authors investigated the relationship between the metabolism of clomipramine (C) and the genotypes of cytochrome P450 (CYP) CYP2C19 and CYP2D6. Fifty-one Japanese patients (18 men and 33 women) were administered 10 to 250 mg/day of C by mouth and maintained on the same daily do...
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