Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CYP3A4 and CYP2C19 genetic polymorphisms and zolpidem metabolism in the Chinese Han population: a pilot study.

Forensic science international - 10 Apr 2013

Shen Min, Shi Yan, Xiang Ping

Abstract excerpt

Zolpidem (ZPD) is an imidazopyridine hypnotic and little is known about the pharmacogenetics of ZPD. Our objective was to evaluate inter-individual genetic variation in conjunction with metabolic ratios of ZPD found in a toxicological analysis. Healthy individuals (n=300) were genotyped for CYP2D6, CYP2C19, CYP2C9, CYP3A4 and CYP1A2 by allele-specific primer extension followed by matrix-assisted laser...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aryl Hydrocarbon Hydroxylases
Share to Chromatography, Liquid
Share to Cytochrome P-450 CYP2C19

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP3A

Share to Hypnotics and Sedatives

Share to Mass Spectrometry

Share to Pilot Projects

Share to Pyridines

Source

Identifiers

PMID: 22964165
DOI: 10.1016/j.forsciint.2012.08.035

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CYP3A4 and CYP2C19 genetic polymorphisms and zolpidem metabolism in the Chinese Han population: a pilot study.PMID 22964165Read ↗

Effects of genetic polymorphisms of CYP2C19 on the pharmacokinetics of zolpidem.Semantic proximity Read ↗

Analysis of 50 SNPs in CYP2D6, CYP2C19, CYP2C9, CYP3A4 and CYP1A2 by MALDI-TOF mass spectrometry in Chinese Han population.Semantic proximity Read ↗

Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation.Semantic proximity Read ↗

Allele, genotype and phenotype frequency distribution of CYP2B6, CYP2C19 and CYP2D6 in Chinese Han populationSemantic proximity Read ↗

Genetic and phenotypic frequency distribution of CYP2C9, CYP2C19 and CYP2D6 in over 3200 Han Chinese.Semantic proximity Read ↗

[The role of CYP2C19 polymorphism in the development of adverse effects to drugs and the risk for diseases].Semantic proximity Read ↗

Meta-analysis of probability estimates of worldwide variation of CYP2D6 and CYP2C19.Semantic proximity Read ↗

Frequencies of CYP2C19 and CYP2D6 gene variants in a German inpatient sample with mood and anxiety disorders.Semantic proximity Read ↗

Prevalence of five pharmacologically most important CYP2C9 and CYP2C19 allelic variants in the population from the Republic of Srpska in Bosnia and Herzegovina.Semantic proximity Read ↗

Application of dried blood spot sampling combined with LC-MS/MS for genotyping and phenotyping of CYP450 enzymes in healthy volunteers.Semantic proximity Read ↗

Association between CYP2C19 and CYP2B6 phenotypes and the pharmacokinetics and safety of diazepam.Semantic proximity Read ↗

Genetic variations of S-mephenytoin 4'-hydroxylase (CYP2C19) in the Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.