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Article

A significant portion of mitochondrial proton leak in intact thymocytes depends on expression of UCP2.

Proceedings of the National Academy of Sciences of the United States of America - 8 Jan 2002

Krauss Stefan, Zhang Chen-Yu, Lowell Bradford B

Abstract excerpt

The uncoupling protein homologue UCP2 is expressed in a variety of mammalian cells. It is thought to be an uncoupler of oxidative phosphorylation. Uncoupling proteins previously have been shown to be capable of translocating protons across phospholipid bilayers in proteoliposome systems. Furthermore, studies in mitochondria from yeast overexpressing the proteins have led to suggestions that they may act as...

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Identifiers

PMID: 11756659
DOI: 10.1073/pnas.012410699
PMCID: PMC117524

Genes

UCP2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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