Article
Preferential loss of maternal 9p alleles in childhood acute lymphoblastic leukemia.
Blood - 1 Jan 2002
Morison Ian M, Ellis Lana M, Teague Lochie R, Reeve Anthony E
Abstract excerpt
Germ-line events, such as paternal mutation or genomic imprinting, contribute to the early onset of childhood cancers such as retinoblastoma, Wilms tumors, and neuroblastoma. Given the high frequency of deletion involving chromosome 9p in childhood acute lymphoblastic leukemia (ALL), this study investigated whether 9p deletion might reflect preexisting germ-line gene inactivation. To do this the parental origin...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.