Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Preferential loss of paternal 19q, but not 1p, alleles in oligodendrogliomas.

Annals of neurology - 1 Jul 2002

Sanson Marc, Leuraud Pascal, Marie Yannick, Delattre Jean-Yves, Hoang-Xuan Khê

Abstract excerpt

Portions of chromosomes 1p and 19q, which are frequently deleted in oligodendrogliomas, are subject to genomic imprinting, suggesting that the putative tumor suppressor genes could be monoallelically expressed. The parental origins of 1p and 19q allele losses were determined in 6 cases of pure oligodendroglioma. An equilibrated parental loss (3 maternal and 3 paternal) was found for 1p deletions. In contrast, 19q...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chi-Square Distribution
Share to Chromosome Deletion
Share to Chromosomes, Human, Pair 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 19

Share to Fathers

Share to Loss of Heterozygosity

Share to Mothers

Share to Oligodendroglioma

Source

Identifiers

PMID: 12112056
DOI: 10.1002/ana.10217

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Preferential loss of paternal 19q, but not 1p, alleles in oligodendrogliomas.PMID 12112056Read ↗

No preferential loss of paternal 19q alleles in oligodendroglial tumors.Semantic proximity Read ↗

The impact of genotype on outcome in oligodendroglioma: validation of the loss of chromosome arm 1p as an important factor in clinical decision making.Semantic proximity Read ↗

Molecular genetic analysis of oligodendroglial tumors shows preferential allelic deletions on 19q and 1p.Semantic proximity Read ↗

Shared allelic losses on chromosomes 1p and 19q suggest a common origin of oligodendroglioma and oligoastrocytoma.Semantic proximity Read ↗

Absence of common somatic alterations in genes on 1p and 19q in oligodendrogliomas.Semantic proximity Read ↗

Oligodendroglial Tumors: Refinement of Candidate Regions on Chromosome Arm 1p and Correlation of 1p/19q Status with SurvivalSemantic proximity Read ↗

Equivalent parental distribution of frequently lost alleles and biallelic expression of the H19 gene in human testicular germ cell tumors.Semantic proximity Read ↗

Chromosomal alterations in oligodendroglial tumours over multiple surgeries: is tumour progression associated with change in 1p/19q status?Semantic proximity Read ↗

Cytogenetic and loss of heterozygosity studies in ependymomas, pilocytic astrocytomas, and oligodendrogliomas.Semantic proximity Read ↗

Pediatric Oligodendrogliomas: A Study of Molecular Alterations on 1p and 19q Using Fluorescence In Situ HybridizationSemantic proximity Read ↗

Oligodendroglioma cell lines containing t(1;19)(q10;p10)Semantic proximity Read ↗

NOTCH2 is neither rearranged nor mutated in t(1;19) positive oligodendrogliomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.