Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Microsatellite instability, MLH-1 promoter hypermethylation, and frameshift mutations at coding mononucleotide repeat microsatellites in ovarian tumors

1 Jan 2001

Abstract excerpt

BACKGROUND: Microsatellite instability (MI) is frequent in endometrial carcinomas (ECs), but its occurrence in ovarian tumors is uncertain. Microsatellite instability positive ECs frequently are associated with frameshift mutations in coding mononucleotide tracts in IGFIIR, BAX, hMSH6, and hMSH3. METHODS: DNA from 52 consecutive patients with ovarian tumors (10 benign, 7 borderline, and 35 malignant) was obtained...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endometrial and Cervical Cancer Treatments
Share to Genetic factors in colorectal cancer
Share to Genomic variations and chromosomal abnormalities

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11753956
DOI: 10.1002/1097-0142(20011201)92:11<2829::aid-cncr10094>3.0.co;2-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Microsatellite instability, MLH-1 promoter hypermethylation, and frameshift mutations at coding mononucleotide repeat microsatellites in ovarian tumorsPMID 11753956Read ↗

Frameshift mutations at coding mononucleotide repeat microsatellites in endometrial carcinoma with microsatellite instabilitySemantic proximity Read ↗

Microsatellite Instability and Epigenetic Inactivation of <i>MLH1</i> and Outcome of Patients With Endometrial Carcinomas of the Endometrioid TypeSemantic proximity Read ↗

Analysis of candidate target genes for mononucleotide repeat mutation in microsatellite instability-high (MSI-H) endometrial cancer.Semantic proximity Read ↗

Frameshift mutations at mononucleotide repeats in caspase-5 and other target genes in endometrial and gastrointestinal cancer of the microsatellite mutator phenotype.Semantic proximity Read ↗

Microsatellite instability and expression of hMLH1 and hMSH2 proteins in ovarian endometrioid cancer.Semantic proximity Read ↗

Microsatellite instability, loss of heterozygosity, and loss of hMLH1 and hMSH2 protein expression in endometrial carcinomaSemantic proximity Read ↗

Frequent LOH at hMLH1, a highly variable SNP in hMSH3, and negligible coding instability in ovarian cancer.Semantic proximity Read ↗

Genes involved in DNA repair are mutational targets in endometrial cancers with microsatellite instability.Semantic proximity Read ↗

Microsatellite instability and alterations in the hMSH2 gene in human ovarian cancer.Semantic proximity Read ↗

Different types of microsatellite instability in ovarian carcinomaSemantic proximity Read ↗

Ovarian tumors display persistent microsatellite instability caused by mutation in the mismatch repair gene hMSH-2.Semantic proximity Read ↗

Mismatch repair gene expression defects contribute to microsatellite instability in ovarian carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.