Article
Frequent LOH at hMLH1, a highly variable SNP in hMSH3, and negligible coding instability in ovarian cancer.
Anticancer research - 1 Jan 2000
Arzimanoglou Iordanis I, Hansen Lise Lotte, Chong David, Li Zhen, Psaroudi Maria C, Dimitrakakis Constantine, Jacovina Andrew T, Shevchuk Maria, Reid Linda, Hajjar Katherine A, Vassilaros Stamatis, Michalas Stylianos, Gilbert Fred, Chervenak Frank A, Barber Hugh R K
Abstract excerpt
BACKGROUND: Molecular alterations such as DNA microsatellite instability (MSI/RER), single nucleotide polymorphism (SNP) and loss of heterozygosity (LOH) can occur throughout the genome and be associated with different types of cancer. In the present study, we aimed at detecting molecular alterat...
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