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Microsatellite Instability and Epigenetic Inactivation of <i>MLH1</i> and Outcome of Patients With Endometrial Carcinomas of the Endometrioid Type

19 May 2007

Abstract excerpt

PURPOSE: Most studies of microsatellite instability (MSI) and outcomes in endometrial cancer patients have included varied histologic subtypes. Nonetheless, MSI occurs almost exclusively in endometrioid tumors. The impact of MSI on outcomes in patients with endometrial cancer is controversial. We sought to determine whether MSI and MLH1 methylation are associated with clinicopathologic variables and survival...

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Share to Endometrial and Cervical Cancer Treatments
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PMID: 17513808
DOI: 10.1200/jco.2006.08.2107

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