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Article

Mismatch repair gene expression defects contribute to microsatellite instability in ovarian carcinoma.

Cancer - 15 Nov 2003

Geisler John P, Goodheart Michael J, Sood Anil K, Holmes Richard J, Hatterman-Zogg Melanie A, Buller Richard E

Abstract excerpt

BACKGROUND: hMLH1, the human MutL homologue, has been linked to microsatellite instability (MSI) in gastrointestinal tumors. However, to the authors' knowledge, the role of hMLH1, the other mismatch repair genes (MMR), and MSI in ovarian carcinoma has not been well defined. The purpose of the cur...

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Share to Adaptor Proteins, Signal Transducing
Share to Base Pair Mismatch
Share to Carcinoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to MutL Protein Homolog 1

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Source

Identifiers

PMID: 14601090
DOI: 10.1002/cncr.11770

Genes

PMS1
PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14601090-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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