Article
Alcohol dehydrogenase type 3 (ADH3) and the risk of bladder cancer.
European urology - 1 Nov 2001
van Dijk B, van Houwelingen K P, Witjes J A, Schalken J A, Kiemeney L A
Abstract excerpt
OBJECTIVES: The polymorphic enzyme alcohol dehydrogenase (ADH) catalyses the conversion of ethanol into the carcinogenic metabolite acetaldehyde which is partly excreted into the urine. Objectives of this pilot study are to determine whether this polymorphism may be related to bladder cancer and whether it modifies the relation between alcohol intake and bladder cancer. METHODS: 120 bladder cancer patients and...
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