Article
Alcohol dehydrogenase 3 genotype modification of the association of alcohol consumption with breast cancer risk.
Cancer causes & control : CCC - 1 Oct 1999
Freudenheim J L, Ambrosone C B, Moysich K B, Vena J E, Graham S, Marshall J R, Muti P, Laughlin R, Nemoto T, Harty L C, Crits G A, Chan A W, Shields P G
Abstract excerpt
OBJECTIVES: Because alcohol dehydrogenase 3 (ADH3) is rate-limiting in alcohol oxidation and is polymorphic, we examined ADH3 genotype in relation to alcohol intake and breast cancer risk. METHODS: We conducted a case-control study among Caucasian women aged 40-85 with incident, pathologically confirmed breast cancer and controls, frequency-matched on age and county. Queries included alcohol intake in the past 20...
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