Histone H3 lysine 4 methylation is mediated by Set1 and required for cell growth and rDNA silencing in Saccharomyces cerevisiae.

doi:10.1101/gad.940201

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Article

Histone H3 lysine 4 methylation is mediated by Set1 and required for cell growth and rDNA silencing in Saccharomyces cerevisiae.

Genes & development - 15 Dec 2001

Briggs S D, Bryk M, Strahl B D, Cheung W L, Davie J K, Dent S Y, Winston F, Allis C D

Abstract excerpt

Histone methylation is known to be associated with both transcriptionally active and repressive chromatin states. Recent studies have identified SET domain-containing proteins such as SUV39H1 and Clr4 as mediators of H3 lysine 9 (Lys9) methylation and heterochromatin formation. Interestingly, H3 Lys9 methylation is not observed from bulk histones isolated from asynchronous populations of Saccharomyces cerevisiae...

Topics

Animals
Antibody Formation
Blotting, Western
Cell Division
DNA Primers
DNA, Bacterial
DNA, Ribosomal
DNA-Binding Proteins
Fungal Proteins
Gene Silencing
Genetic Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Heterochromatin

Histone Methyltransferases

Histone-Lysine N-Methyltransferase

Histones

Lysine

Methylation

Methyltransferases

Source

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Identifiers

PMID: 11751634
DOI: 10.1101/gad.940201
PMCID: PMC312847

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-11751634-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Histone H3 lysine 4 methylation is mediated by Set1 and required for cell growth and rDNA silencing in Saccharomyces cerevisiae.PMID 11751634Read ↗

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