Article
Silencing in yeast: identification of clr4 targets.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2006
Ivanov Sergey V, Ivanova Alla V
Abstract excerpt
Efficient handling of multiple reactions is a crucial prerequisite for productive RNA differential display (DD) analysis. To identify transcriptional targets of the histone H3 Lys9-specific methyltransferase Clr4, we applied a multiformat modification of DD to compare between clr4+ and clr4- transcriptomes of Schizosaccaromyces pombe. As a result, 14 differentially expressed bands were identified among 720...
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