Genetic and genomewide analysis of simultaneous mutations in acetylated and methylated lysine residues in histone H3 in Saccharomyces cerevisiae.

doi:10.1534/genetics.108.098897

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Article

Genetic and genomewide analysis of simultaneous mutations in acetylated and methylated lysine residues in histone H3 in Saccharomyces cerevisiae.

Genetics - 1 Feb 2009

Jin Yi, Rodriguez Amy M, Wyrick John J

Abstract excerpt

Acetylated and methylated lysine residues in histone H3 play important roles in regulating yeast gene expression and other cellular processes. Previous studies have suggested that histone H3 acetylated and methylated lysine residues may functionally interact through interdependent pathways to regulate gene transcription. A common genetic test for functional interdependence is to characterize the phenotype of a...

Topics

Acetylation
Gene Expression Profiling
Gene Expression Regulation, Fungal
Genome, Fungal
Genome-Wide Association Study
Histones
Lysine
Methylation
Mutagenesis, Site-Directed
Mutation
Oligonucleotide Array Sequence Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

RNA, Fungal

RNA, Messenger

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Telomere

Source

Open in PubMed Open full text

Identifiers

PMID: 19087956
DOI: 10.1534/genetics.108.098897
PMCID: PMC2644940

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-19087956-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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