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Article

Differential DNA methylation between fetus and mother as a strategy for detecting fetal DNA in maternal plasma.

Clinical chemistry - 1 Jan 2002

Poon Leo L M, Leung Tse N, Lau Tze K, Chow Katherine C K, Lo Y M Dennis

Abstract excerpt

BACKGROUND: Fetal DNA has been detected in maternal plasma by the use of genetic differences between mother and fetus. We explore the possibility of using epigenetic markers for the specific detection of fetal DNA in maternal plasma. METHODS: A differentially methylated region in the human IGF2-H19 locus and a single-nucleotide polymorphism in this region were chosen for the study. The methylation status in this...

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Identifiers

PMID: 11751536

Genes

IGF2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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