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Fetal DNA in Maternal Plasma: Biology and Diagnostic Applications

1 Dec 2000

Abstract excerpt

BACKGROUND: Molecular analysis of plasma DNA during human pregnancy has led to the discovery that maternal plasma contains both fetal and maternal DNA. This valuable source of fetal DNA opens up new possibilities for noninvasive prenatal diagnosis. APPROACH: Published data from the last 3 years demonstrating the feasibility and utility of analyzing fetal DNA in maternal plasma are reviewed. CONTENT: The detection...

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Share to Blood groups and transfusion
Share to Pregnancy and preeclampsia studies
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 11106320
DOI: 10.1093/clinchem/46.12.1903

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