Article
Polymorphism of the 5-HT1B receptor gene (HTR1B): strong within-locus linkage disequilibrium without association to antisocial substance dependence.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jan 2002
Kranzler Henry R, Hernandez-Avila Carlos A, Gelernter Joel
Abstract excerpt
UNLABELLED: Serotonergic abnormalities may be present in individuals with either substance dependence (SD) or antisocial personality disorder (ASPD), disorders that occur together commonly. Consequently, genes encoding serotonin (5-HT) receptors are candidates for genetic studies of both disorders. found evidence for linkage of antisocial alcoholism to HTR1B (the locus encoding the 5-HT1B receptor) in both Finns...
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