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Article

Interaction between serotonin transporter and serotonin receptor 1 B genes polymorphisms may be associated with antisocial alcoholism.

Behavioral and brain functions : BBF - 11 Jul 2012

Wang Tzu-Yun, Lee Sheng-Yu, Chen Shiou-Lan, Chang Yun-Hsuan, Chen Shih-Heng, Chu Chun-Hsien, Huang San-Yuan, Tzeng Nian-Sheng, Wang Chen-Lin, Lee I Hui, Yeh Tzung Lieh, Yang Yen Kuang, Lu Ru-Band

Abstract excerpt

BACKGROUND: Several studies have hypothesized that genes regulating the components of the serotonin system, including serotonin transporter (5-HTTLPR) and serotonin 1 B receptor (5-HT1B), may be associated with alcoholism, but their results are contradictory because of alcoholism's heterogeneity. Therefore, we examined whether the 5-HTTLPR gene and 5-HT1B gene G861C polymorphism are susceptibility factors for a...

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Identifiers

PMID: 22550993
DOI: 10.1186/1744-9081-8-18
PMCID: PMC3583294

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