Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CNR1 variation modulates risk for drug and alcohol dependence.

Biological psychiatry - 15 Sept 2007

Zuo Lingjun, Kranzler Henry R, Luo Xingguang, Covault Jonathan, Gelernter Joel

Abstract excerpt

BACKGROUND: Human cannabinoid receptor 1 (CB1), which is encoded by the CNR1 gene, may play a role in the development of substance dependence (SD). Following initial reports of association of CNR1 with SD, we studied multiple markers at this locus in a large case-control sample. METHODS: Ten CNR1 markers and 38 ancestry-informative markers were genotyped in 451 healthy control subjects and 550 SD (AD and/or DD)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcoholism
Share to Black or African American
Share to Comorbidity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Markers

Share to Receptor, Cannabinoid, CB1

Share to Regression Analysis

Share to Substance-Related Disorders

Share to White People

Source

Identifiers

PMID: 17509535
DOI: 10.1016/j.biopsych.2006.12.004

Genes

CNR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CNR1 variation modulates risk for drug and alcohol dependence.PMID 17509535Read ↗

Cannabinoid receptor 1 gene is associated with alcohol dependence.Semantic proximity Read ↗

Associations of CB1 cannabinoid receptor (CNR1) gene polymorphisms with risk for alcohol dependence: Evidence from meta-analyses of genetic and genome-wide association studies.Semantic proximity Read ↗

Cannabinoid receptor 1 gene association with nicotine dependence.Semantic proximity Read ↗

Interaction between two independent CNR1 variants increases risk for cocaine dependence in European Americans: a replication study in family-based sample and population-based sample.Semantic proximity Read ↗

Common single nucleotide variants underlying drug addiction: more than a decade of research.Semantic proximity Read ↗

Human cannabinoid receptor 1: 5' exons, candidate regulatory regions, polymorphisms, haplotypes and association with polysubstance abuse.Semantic proximity Read ↗

The OPRD1 and OPRK1 loci in alcohol or drug dependence: OPRD1 variation modulates substance dependence risk.Semantic proximity Read ↗

CNR1 gene polymorphisms in addictive disorders: a systematic review and a meta-analysis.Semantic proximity Read ↗

Evidence for association between polymorphisms in the cannabinoid receptor 1 (CNR1) gene and cannabis dependence.Semantic proximity Read ↗

Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.Semantic proximity Read ↗

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.Semantic proximity Read ↗

The incentive salience of alcohol: translating the effects of genetic variant in CNR1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.