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Article

Linkage of antisocial alcoholism to the serotonin 5-HT1B receptor gene in 2 populations.

Archives of general psychiatry - 1 Nov 1998

Lappalainen J, Long J C, Eggert M, Ozaki N, Robin R W, Brown G L, Naukkarinen H, Virkkunen M, Linnoila M, Goldman D

Abstract excerpt

BACKGROUND: In mice, quantitative trait locus studies and behavioral evaluation of animals deleted for 5-HT1B have implicated this serotonin autoreceptor in alcohol consumption and aggressive behavior. We therefore investigated whether the 5-HT1B gene (HTR1B) is linked to alcoholism with aggressive and impulsive behavior in the human, as represented by 2 psychiatric diagnoses: antisocial personality disorder and...

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Identifiers

PMID: 9819067
DOI: 10.1001/archpsyc.55.11.989

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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