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Article

Mutational analysis of the beta-tubulin gene in lung cancer.

Lung cancer (Amsterdam, Netherlands) - 1 Jan 2002

Tsurutani Junji, Komiya Takefumi, Uejima Hisao, Tada Hirohito, Syunichi Negoro, Oka Mikio, Kohno Shigeru, Fukuoka Masahiro, Nakagawa Kazuhiko

Abstract excerpt

Recently, several studies have suggested that a major mechanism of resistance to paclitaxel might involve mutations in the beta-tubulin gene in tumor cells. To investigate the frequency of beta-tubulin mutations in Japanese patients with small and non-small cell lung cancer, direct sequence analysis following reverse transcription-polymerase chain reaction (RT-PCR) of the beta-tubulin gene was performed using...

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PMID: 11750707
DOI: 10.1016/s0169-5002(01)00291-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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