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Article

Absence of beta-tubulin gene mutation in gastric carcinoma.

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association - 1 Jan 2003

Urano Naomi, Fujiwara Yoshiyuki, Hasegawa Seiichi, Miyoshi Yasuo, Noguchi Shinzaburo, Takiguchi Shuji, Yasuda Takushi, Yano Masahiko, Monden Morito

Abstract excerpt

BACKGROUND: Effective chemotherapy for advanced gastric cancer is yet to be established. Taxanes, novel anticancer drugs which bind to beta-tubulin and prevent disruption of microtubules, are newly approved and promising agents for advanced and recurrent gastric cancer. To predict the chemoresistance to a taxan in gastric cancer, we examined the genetic mutations of the beta-tubulin gene. METHODS: Fifty pairs of...

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Identifiers

PMID: 12861402
DOI: 10.1007/s10120-003-0235-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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