Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of beta-tubulin gene alteration in human lung cancer cell lines.

Cancer letters - 25 Nov 2003

Achiwa Hiroyuki, Sato Shigeki, Shimizu Shigeki, Maeda Hiroyoshi, Niimi Takashi, Takahashi Takashi, Ueda Ryuzo, Mitsudomi Tetsuya

Abstract excerpt

We examined lung cancer cell lines for the presence of beta-tubulin gene alteration based on a previous report of a relationship between frequent beta-tubulin gene mutation in non-small-cell lung cancer and clinical response to taxanes as well as the prognosis. The mutation was defined by analyzing genomic DNA from 31 lung cancer cell lines by direct genomic sequencing using specific primers for the beta-tubulin...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Codon
Share to DNA Primers
Share to Exons

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Introns

Share to Lung Neoplasms

Share to Polymorphism, Single-Stranded Conformational

Share to Tubulin

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 14607336
DOI: 10.1016/s0304-3835(03)00473-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of beta-tubulin gene alteration in human lung cancer cell lines.PMID 14607336Read ↗

Mutational analysis of the class I β‐tubulin gene in human breast cancerSemantic proximity Read ↗

Mutational analysis of the beta-tubulin gene in lung cancer.Semantic proximity Read ↗

Paclitaxel resistance in non-small-cell lung cancer associated with beta-tubulin gene mutations.Semantic proximity Read ↗

Conservation of the class I beta-tubulin gene in human populations and lack of mutations in lung cancers and paclitaxel-resistant ovarian cancers.Semantic proximity Read ↗

Do beta-tubulin mutations have a role in resistance to chemotherapy?Semantic proximity Read ↗

Genetic analysis of the beta-tubulin gene, TUBB, in non-small-cell lung cancer.Semantic proximity Read ↗

Absence of beta-tubulin gene mutation in gastric carcinoma.Semantic proximity Read ↗

Class III β-Tubulin Mediates Sensitivity to Chemotherapeutic Drugs in Non–Small Cell Lung CancerSemantic proximity Read ↗

Mutation of the class I beta-tubulin gene does not predict response to paclitaxel for breast cancer.Semantic proximity Read ↗

Cytoskeleton and paclitaxel sensitivity in breast cancer: the role of beta-tubulins.Semantic proximity Read ↗

Direct analysis of tubulin expression in cancer cell lines by electrospray ionization mass spectrometry.Semantic proximity Read ↗

Expression of excision repair cross-complementation group 1 and class III beta-tubulin predict survival after chemotherapy for completely resected non-small cell lung cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.