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Article

Post-translational modifications of mitochondrial aldehyde dehydrogenase and biomedical implications.

Journal of proteomics - 18 Nov 2011

Song Byoung-Joon, Abdelmegeed Mohamed A, Yoo Seong-Ho, Kim Bong-Jo, Jo Sangmee A, Jo Inho, Moon Kwan-Hoon

Abstract excerpt

Aldehyde dehydrogenases (ALDHs) represent large family members of NAD(P)+-dependent dehydrogenases responsible for the irreversible metabolism of many endogenous and exogenous aldehydes to the corresponding acids. Among 19 ALDH isozymes, mitochondrial ALDH2 is a low Km enzyme responsible for the metabolism of acetaldehyde and lipid peroxides such as malondialdehyde and 4-hydroxynonenal, both of which are highly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21609791
DOI: 10.1016/j.jprot.2011.05.013
PMCID: PMC3177986

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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