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Article

Alterations on the 5' noncoding region of the BCL-6 gene are not correlated with BCL-6 protein expression in T cell non-Hodgkin lymphomas.

Laboratory investigation; a journal of technical methods and pathology - 1 Dec 2001

Kerl K, Vonlanthen R, Nagy M, Bolzonello N J, Gindre P, Hurwitz N, Gudat F, Nador R G, Borisch B

Abstract excerpt

The BCL-6 proto-oncogene is expressed in germinal center B lymphocytes, in their neoplastic counterparts, and in a subpopulation of germinal center and perifollicular T lymphocytes. Rearrangements and/or mutations of the 5' noncoding region of the bcl-6 gene have been demonstrated in a large majority of diffuse large B cell lymphomas. Some, but not all, of these genetic alterations lead to dysregulation of the...

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PMID: 11742039
DOI: 10.1038/labinvest.3780382

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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