Article
Low incidence of BCL-6 gene alterations for diffuse large B-cell lymphomas in Taiwan Chinese.
Cancer - 15 May 2002
Chen Po-Min, Yang Muh-Hwa, Yu I-Ting, Lin Jen-Tsun, Lin Yu-Chen, Fan Frank S, Wang Wei-Shu, Yen Chueh-Chuan, Chiou Tzeon-Jye, Liu Jin-Hwang
Abstract excerpt
BACKGROUND: In Western populations, rearrangement of the BCL-6 gene can be identified in 20-40% of patients with diffuse large B-cell lymphoma (DLBCL). Analysis of the BCL-6 gene has revealed the presence of point mutations or small deletions in 70% of DLBCL tumors; however, few studies have investigated BCL-6 gene alteration in patients with non-Hodgkins lymphoma (NHL) of Chinese descent. METHODS: Samples from...
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