Article
Biallelic DNA rearrangements and deletions within the BCL-6 gene in B-cell non-Hodgkin's lymphoma.
British journal of haematology - 1 Jun 1995
Nakamura Y, Miki T, Kawamata N, Hirosawa S, Saito K, Enokihara H, Furusawa S, Shishido H
Abstract excerpt
Chromosomal translocations involving band 3q27 are recently described common specific cytogenetic abnormalities in B-cell neoplasms, and the BCL-6 gene, identified on 3q27, was shown to be disrupted and over-expressed in lymphoma cells having these chromosomal translocations. In the present study we found rearrangements within the BCL-6 gene in seven out of 35 cases with B-cell non-Hodgkin's lymphoma (NHL)....
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