Article
Mastoparan stimulates GABA release from MIN6 cells: relationship between SNARE proteins and mastoparan action.
Biochemical and biophysical research communications - 21 Dec 2001
Ohara-Imaizumi M, Nakamichi Y, Ozawa S, Katsuta H, Ishida H, Nagamatsu S
Abstract excerpt
We examined the action of mastoparan on beta cell exocytosis. Mastoparan stimulated GABA and insulin release from MIN6 beta cells. On the other hand, mastopraran-induced GABA release was decreased by expressing the tetanus toxin C1 light chain in MIN6 cells. We have then investigated the relationship between SNARE proteins and mastoparan action using adenovirus-mediated gene transfer system. Overexpression of...
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