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Botulinum Neurotoxins beyond Neurons: Interplay with Glial Cells

13 Oct 2022

Abstract excerpt

In recent years, numerous studies have highlighted the significant use of botulinum neurotoxins (BoNTs) in the human therapy of various motor and autonomic disorders. The therapeutic action is exerted with the selective cleavage of specific sites of the SNARE's protein complex, which plays a key role in the vesicular neuroexocytosis which is responsible for neural transmission. The primary target of the BoNTs'...

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PMID: 36287971
DOI: 10.3390/toxins14100704

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