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Article

Likelihood formulation of parent-of-origin effects on segregation analysis, including ascertainment.

American journal of human genetics - 1 Jan 2002

Haghighi Fatemeh, Hodge Susan E

Abstract excerpt

We developed a likelihood-based method for testing for parent-of-origin effect in complex diseases. The likelihood formulations model parent-of-origin effect and allow for incorporation of ascertainment, as well as differential male and female ascertainment probabilities. The results based on simulated data indicated that the estimates of parental effect (either maternal or paternal) were biased when...

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Identifiers

PMID: 11741195
DOI: 10.1086/324709
PMCID: PMC384884

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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