Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of IGF-I and IGFBPs in the changes of mass and phenotype induced in rat soleus muscle by clenbuterol.

American journal of physiology. Endocrinology and metabolism - 1 Jan 2002

Awede Bonaventure L, Thissen Jean-Paul, Lebacq Jean

Abstract excerpt

Clenbuterol induces hypertrophy and a slow-to-fast phenotype change in skeletal muscle, but the signaling mechanisms remain unclear. We hypothesized that clenbuterol could act via local expression of insulin-like growth factor I (IGF-I). Administration of clenbuterol to 3-mo-old female Wistar rats resulted in a 10 and 13% increase of soleus muscle mass after 3 and 9 days, respectively, reaching 16% after 4 wk....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenergic beta-Agonists
Share to Blood

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Insulin-Like Growth Factor Binding Proteins

Share to Insulin-Like Growth Factor I

Share to Myosin Heavy Chains

Share to Organ Size

Share to Peptide Fragments

Share to Rats, Wistar

Source

Identifiers

PMID: 11739080
DOI: 10.1152/ajpendo.2002.282.1.E31

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of IGF-I and IGFBPs in the changes of mass and phenotype induced in rat soleus muscle by clenbuterol.PMID 11739080Read ↗

Clenbuterol induces hypertrophy of the latissimus dorsi muscle and heart in the rat with molecular and phenotypic changes.Semantic proximity Read ↗

Fibroblast growth factor-21 induces skeletal muscle atrophy and increases plasma amino acids in female mice: a potential role for glucocorticoidsSemantic proximity Read ↗

Minireview: Mechano-Growth Factor: A Putative Product of IGF-I Gene Expression Involved in Tissue Repair and RegenerationSemantic proximity Read ↗

Effects of chronic administration of clenbuterol on contractile properties and calcium homeostasis in rat extensor digitorum longus muscle.Semantic proximity Read ↗

Thyroid hormone receptor-beta-selective agonist GC-24 spares skeletal muscle type I to II fiber shift.Semantic proximity Read ↗

The ciliary neurotrophic factor induces Stat3 phosphorylation in distinctive cytotypes of organs involved in body metabolism: an immunohistochemical studySemantic proximity Read ↗

Calpastatin overexpression in the skeletal muscle of mice prevents clenbuterol-induced muscle hypertrophy and phenotypic shift.Semantic proximity Read ↗

Gene expression in muscle in response to exercise.Semantic proximity Read ↗

Influence of overload on phenotypic remodeling in regenerated skeletal muscle.Semantic proximity Read ↗

IGF-I activates the mouse type IIb myosin heavy chain gene.Semantic proximity Read ↗

Influences of IGF-I gene disruption on the cellular profile of the diaphragm.Semantic proximity Read ↗

Calcineurin Is Required for Skeletal Muscle HypertrophySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.