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Article

Thyroid hormone receptor-beta-selective agonist GC-24 spares skeletal muscle type I to II fiber shift.

Cell and tissue research - 1 Aug 2005

Miyabara Elen H, Aoki Marcelo S, Soares Antonio G, Saltao Rodrigo M, Vilicev Cassio M, Passarelli Marisa, Scanlan Thomas S, Gouveia Cecilia H, Moriscot Anselmo S

Abstract excerpt

Triiodothyronine (T3) is known to play a key role in the function of several tissues/organs via the thyroid hormone receptor isoforms alpha (TRalpha) and beta (TRbeta). We have investigated the effects of GC-24, a novel synthetic TRbeta-selective compound, on skeletal muscle fiber-type determination, cross-sectional area, and gene expression in rat skeletal muscles. For fiber typing, cross sections of soleus and...

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Identifiers

PMID: 15947969
DOI: 10.1007/s00441-005-1119-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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