Article
Effects of chronic administration of clenbuterol on contractile properties and calcium homeostasis in rat extensor digitorum longus muscle.
PloS one - 1 Jan 2014
Sirvent Pascal, Douillard Aymerick, Galbes Olivier, Ramonatxo Christelle, Py Guillaume, Candau Robin, Lacampagne Alain
Abstract excerpt
Clenbuterol, a β2-agonist, induces skeletal muscle hypertrophy and a shift from slow-oxidative to fast-glycolytic muscle fiber type profile. However, the cellular mechanisms of the effects of chronic clenbuterol administration on skeletal muscle are not completely understood. As the intracellular Ca2+ concentration must be finely regulated in many cellular processes, the aim of this study was to investigate the...
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